Cape Romain Wilderness Area is located at the eastern coast facing the Atlantic Ocean. The southern tip of the wilderness is approximately 8 miles northeast of Charleston, SC. The wilderness is part of the 64,229 acre Cape Romain National Wildlife Refuge. The wilderness area consists of 28,000 acres of beach and salt water bays, salt marshes, sand dunes, maritime forests, tidal creeks,  fresh and brackish water impoundments, and parts of open water. The IMPROVE site is located in a clearing near the visitor center at the refuge's maintenance yard. The nearest highway is highway 17, 2.2 miles to the west. The IMPROVE site is located at an elevation of 5 m MSL. The state of South Carolina Department of Health and Environmental Control operates an ozone, PM2.5, PM10 and meteorological station within close proximity of the IMPROVE site.